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Product Description:
Caffeine is perhaps the most widely used agent to mobilize fat for use
as fuel, and one that actually helps burn that fat by elevating energy
expenditure (basal metabolic rate). Several studies have shown that
caffeine promotes lipolysis, the breakdown of stored fats into fatty
acids which can be used by working muscle and other tissues for fuel
while sparing glycogen in the process.
The traditional theory on
how caffeine promotes lipolysis rests on the fact that at relatively
high concentrations caffeine acts as a phophodiesterase inhibitor,
maintaining elevated levels of cAMP (cyclic AMP) and in the process
amplifying the effects of the body’s natural lipolytic hormones
epinephrine and norepinephrine.
During the lipolytic (fat
mobilizing) signaling cascade, natural hormones like norepinephrine and
epinephrine (or synthetic analogs like ephedrine or clenbuterol) bind to
so-called alpha-1 and beta-1 and beta-2 adrenergic receptors on the
surface of fat cells, activating cyclic Adenosine Monophosphate, or
cAMP. cAMP ultimately acts to turn on the enzyme Hormone Sensitive
Lipase (HSL). HSL breaks up stored fat so that it can be used for fuel.
In
addition, cAMP is deactivated by an enzyme called phosphodiesterase.
Caffeine inhibits the action of phospodiesterase thereby prolonging
lipolysis. Besides acting as a cutting agent, caffeine possesses
ergogenic (sports performance enhancing) properties. The fat
burning/glycogen sparing effect above may contribute to this.
Benefits
• Promotes lipolysis (the breakdown of stored fats) so they can be burned for energy
• Promotes increased exercise performance and endurance
• Spares glycogen (the muscle’s sugar energy stores)
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